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According to an article published Wednesday in JAMA, leading U.S. medical journal MERCK prepared research studies for their best-selling pain drug Vioxx that were reviewed by prominent physicians prior to being submitted for publication in medical journals. JAMA used documents from litigation over this drug as the source for this rare look into a practice known as hiring professional writers to draft early drafts of scientific papers for publication.

Merck used nine studies involving patients at low cardiovascular risk whose results were used by it to promote Vioxx’s heart attack risks; these studies, however, contained numerous flaws due to short treatment duration periods, small patient populations and insufficient data regarding effectiveness against heart attacks or strokes.